Replication DNA.swf / DNA Replikasi.swf

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• DNA replication begins with the "unzipping" of the parent molecule as the hydrogen bonds between the base pairs are broken.
• Once exposed, the sequence of bases on each of the separated strands serves as a template to guide the insertion of a complementary set of bases on the strand being synthesized.
• The new strands are assembled from deoxynucleoside triphosphates.
• Each incoming nucleotide is covalently linked to the "free" 3' carbon atom on the pentose (figure) as
• the second and third phosphates are removed together as a molecule of pyrophosphate (PPi).
• The nucleotides are assembled in the order that complements the order of bases on the strand serving as the template.
• Thus each C on the template guides the insertion of a G on the new strand, each G a C, and so on.
• When the process is complete, two DNA molecules have been formed identical to each other and to the parent molecule.